effects of exercise on expression of CYP19 and StAR mRNA in steroid-induced polycystic ovaries of female rats

ABSTRACT

Background: Polycystic ovarian syndrome [PCOS] is the most frequent female endocrine disorder that affects 5-10% of women. PCOS is characterized by hyperandrogenism, oligo-/anovulation, and polycystic ovaries. The aim of the present research is to evaluate the expression of steroidogenic acute regulatory protein [StAR] and aromatase [CYP19] mRNA in the ovaries of an estradiol valerate [EV]-induced PCOS rat model, and the effect of treadmill and running wheel [voluntary] exercise on these parameters