Relationship between human leukocyte antigen [HLA]-DQA1*0102/HLA-DQB1*0602 polymorphism and preeclampsia

ABSTRACT

Background: Preeclampsia is a condition associated with systemic disorders in the mother and the fetus. However, the exact causes of preeclampsia are unknown, but several genetics and environmental factors play role in development of this disease. Major histocompatibility complex role is very important during pregnancy through which the fetus is not rejected by mother's immune system