effect of GABA A receptor antagonist bicucullin administration on the number of multiform neurons in the brain parabrachial nucleus due to pain induction of adult male rats

ABSTRACT

Background and Aim: A lot of biological investigations are aimed to find pain decreasing or relieving substances that appear in various diseases. Parabrachial nucleus plays an important role in cognitive and emotional aspects of pain. The present study was designed to evaluate the inhibitory effect of bicuculine- as a GABA A receptor antagonist- on the number of multiform neurons in Parabrachial region of adult male rats in tonic pain model