Combined low dose aspirin and 17 alpha hydroxyl progesterone versus 17 alpha hydroxyl progesterone alone study in pregnancy: a randomized clinical trial for prevention of spontaneous preterm birth
Egyptian Journal of Hospital Medicine [The]. 2018; 71 (4): 2932-2943
em Inglês
| IMEMR
| ID: emr-192549
ABSTRACT
Background:
Preterm birth defined as any live birth occurring through the end of the last day of the 37th week [259th day] following the onset of the last menstrual period. Low-dose aspirin [LDA] has been noted to reduce the preterm birth [PTB] rate in multiple meta-analyses of the preeclampsia [PreE] prevention trials. It is unclear if this effect of LDA is entirely due to a reduction in indicated PTB versus reductions in preterm premature rupture of membranes [PPROM] or spontaneous PTB. In the Maternal-Fetal Medicine Unit [MFMU] high-risk aspirin [HRA] study, a near significant decrease in PTB was found despite no effect on preeclampsia. The objective of this study was to assess the impact of LDA on indicated PTB, spontaneous PTB, and PPROM PTB in the MFMU HRA study population
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Gravidez
/
Aspirina
/
Método Duplo-Cego
/
17-alfa-Hidroxiprogesterona
/
Gestantes
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Egypt. J. Hosp. Med.
Ano de publicação:
2018
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