Evaluation of split course and continuous radiation therapy in inoperable non small cell bronchial carcinoma

ABSTRACT

This study included 192 patients with inoperable non small cell bronchial carcinoma treated radically by irradiation at Faculty of Medicine, University of Alexandria between 1980 to 1989. Two treatment protocols were used in group A, a split- course in 71 patients and 121 patients in group B, continuous course radiation therapy. NSD and BED values were calculated for both treatment groups and were correlated with response and treatment morbidities. The overall [CR+PR] were 34/55 [34/55 [62%] in group A versus 50.75 [67%] in group B. The difference was not statistically significant [P > 0.05]. The two years survival rate was 13/31 [42%] relatively higher in group A compared to 17/47 [36%] in group B, but the difference was not statistically significant. The morbidities were nearly equal in both treatment groups