Impact of blood groups on the biochemical response to some occupational pollutants

ABSTRACT

The present study was carried out. aiming to investigate the role of the ABO blood group distribution on some biochemical changes among workers exposed to occupational toxicants. For this purpose, a total number of 118 workers exposed to CS[2] and 89 workers exposed to Pb were selected. A comparison group was also included [n=100]. Fasting blood samples were collected and the levels of FBS,GGT, ALP, creatinine, total lipids, TG, Ch, Ph, LDL, VLDL, HDL, bleeding time, clotting time and prothrombin time were determined. Also, from spot urine samples, the levels of ALAU and the I[2] N[3] test were assessed. By comparing the results among the different blood groups, it was found that some biochemical changes are blood group dependent. Individual! of blood group Bhad the more pronounced atherogenic effect of both CS[2] and Pb exposure than others. Therefore, the present study supports the hypothesis of the role of blood group specificity in biological responses to toxic agents