Recent advancements in the clinical use of aspirin

ABSTRACT

Aspirin [acetylsalicylic acid] is a widely used drug that possesses analgesic activity. It is effective in the treatment of pain, inflammation and fever. In addition to these ailments aspirin has been found to be useful in the treatment of other diseases including cell apoptosis and colorectal cancer, Kawasaki disease, migraine and cardiovascular diseases. The mechanism of action of aspirin is due to its ability to suppress the production of prostaglandin and thromboxanes as a result of its irreversible inactivation of cyclo-oxygenase [COX] enzyme