Role of anti-CCP in diagnosis of rheumatoid arthritis in comparison to rheumatoid factor

ABSTRACT

Background: RA is a chronic inflammatory disease that primarily affects the diarthroidal joints. Persistence and progression of the disease is regulated by immune mediators that continue to be defined and provide targets for immune intervention. Anti-CCP Antibodies were detected in over 80% of RA sera. This serological test has advantage of easy performance by convenient enzyme linked immunosorbent assay test