Synthesis of polyfunctionally substituted 5,6,7,8 tetrahydroquinolines and several condensed azines
Egyptian Journal of Chemistry. 2006; 49 (5): 575-588
em Inglês
| IMEMR
| ID: emr-196188
ABSTRACT
2-amino-3-cyano-4-phenyl-5,6,7,8-tetrahydroquanoline [3] and other related new quinolones were synthesized and submitted to evaluation for their anti-microbial activity. Compound [3] was prepared by reaction of cyclohexanone, arylidines malononitrile and amm. acetate. Other reagents were studied as the nature of the nuceolophile and reaction conditions. The behaviour of some products towards carbon electrophiles, e.g. acid chlorides, acid anhydrides and alkylating agents has been discussed
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Índice:
IMEMR (Mediterrâneo Oriental)
Idioma:
Inglês
Revista:
Egypt. J. Chem.
Ano de publicação:
2006
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