Platelet monoamine oxidase activity in schizophrenia

ABSTRACT

Platelet monoamine oxidase activity was assessed in 50 schizophrenics and 30 controls. The platelet MAO activity was significantly lower in schizophrenics compared to controls. There was no significant difference between paranoid and disorganized schizophrenics regarding platelet MAO activity. Schizophrenics with negative symptoms showed significantly lower platelet MAO activity than those with positive symptoms. The platelet MAO activity in patients with positive family history of schizophrenia was significantly lower than schizophrenics with negative family history