Synthesis of some new quinoline-mannich bases and other related products of possible antimicrobial activity

ABSTRACT

The synthesis of thirteen new quinoline-Mannich bases and 1,2,4- triazolo [4,3-a] quinolines was reported. These include four intermediates and nine final new compounds. The chemical structures of these compounds were confirmed by elemental and spectral analyses. Two representative compounds were tested for antimicrobial and antifungal activities. The results obtained indicated that the tested compounds possess a potent antimicrobial activity and lower antifungal properties