Interleukin 10 gene polymorphism in hemodialysis patients: association with biological and nutritional markers and indices of function and comorbidity

ABSTRACT

Background: There are considerable evidences for a cytokine orchestrated chronic inflammatory response in long term hemodialysis patients. It is possible that genetically determined lower production of IL-10 might influence disease susceptibility and or severity caused by altered proinflammatory antiinflammatory cytokine balance