Studies on alkyl heterocyclic aromatic compounds new routes for the synthesis of azanaphthalene

ABSTRACT

Synthesis of pyridine derivatives via reaction of 2-amino-1,1,3-tricyanoprop-1-ene with trichloroacetonitrile or diethyl-malonomonoimidate hydrochloride has been achieved. Compounds 3a,b coupled with aryldiazonium chloride to yield the corresponding coupling products 4a-d. Compounds 4c-d could be converted into 6a-b on treated with acetic acid. The reaction of 3b with acetic hydrochloric acid mixture and trichloro acetonitrile are reported