Thymoquinone ameliorates some endocrine parameters and histological alteration in a rat model of polycystic ovary syndrome

ABSTRACT

Background: Polycystic ovary syndrome [PCOS] is a common form of the endocrine disease which is associated with metabolic dysfunction. PCOS and type 2 diabetes mellitus are related in multiple aspects and are similar in many pathological features. Anti-diabetic effects of Nigella sativa and protective effects of it on reproductive system have been suggested in some reports