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Effects of Costus speciosus ethanolic extract on male rats: the action mechanism and the ability to impregnate
Pakistan Journal of Pharmaceutical Sciences. 2018; 31 (3 Supp.): 997-1001
em Inglês | IMEMR | ID: emr-198709
ABSTRACT
To examine the action mechanism that mediates the anti-fertility effect of Costus speciosus extract, research was conducted on male Sprague-Dawley rats. Costus extract was given to male rats for 14 days at various doses, namely 275, 550 and 1,100 mg kg-1 day-1 in 0.5% sodium CMC. The results showed that Costus extract with doses ranging from 275 to 1,100 mg kg-1 day-1 was able to inhibit pregnancy among female rats by 10-70%. No obstacles in terms of sexual behavior were identified among male rats. The anti-fertility effect of Costus extract kicked in without involving a decreased level of male reproductive hormones
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Índice: IMEMR (Mediterrâneo Oriental) Idioma: Inglês Revista: Pak. J. Pharm. Sci. Ano de publicação: 2018

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Índice: IMEMR (Mediterrâneo Oriental) Idioma: Inglês Revista: Pak. J. Pharm. Sci. Ano de publicação: 2018