Sideroblastic anaemia as a diagnostic filch point of melas [myoencephalopathy, lactic acidosis and stroke like episodes]

ABSTRACT

Sideroblastic anaemia includes a heterogeneous group of conditions characterized by decreased heme synthesis and mitochondrial iron overload. It is diagnosed by the presence of ringed sideroblasts in the bone marrow aspirate and association of this form of anemia with various mitochondrial dysfunction disorders can be a catch point to reach an ultimate diagnosis in these disorders as reported in this case of myoencephalopathy, lactic acidosis, and stroke-like episodes [MELAS] syndrome