Comparison of atherogenic index and lipid profiles in candidates for coronary artery bypass graft surgery versus normal people

ABSTRACT

Information on incidence and risk factors of cardiovascular disease [CVD] is rare in the Middle East. This study aims to compare Iranian candidates for coronary artery bypass graft [CABG] surgery and healthy controls in terms of lipid profile, atherogenic index of plasma [AIP], and atherosclerosis index [ASTI]. The individuals recruited in this study were 135 CVD patients before CABG surgery and 135 healthy subjects matching in age with the cases. Lipid profiles of the two groups were analyzed with a commercial kit. The AIP and ASTI indexes were calculated with related formula. The TC, TG, LDL-C and HDL-c parameters were dramatically changed [p<0.01] between study groups. AIP and ASTI indexes were significantly higher in patients than in healthy people [p=0.001]. In individuals with CVD, it is suggested to measure these indexes in order for effective diagnosis before CABG surgery