Comparison of the melatonin preconditioning efficacy between bone marrow and Adipose-Derived mesenchymal stem cells

ABSTRACT

Objective: Mesenchymal stem cells [MSC] from various sources have the potentials to positively affect regenerative medicine.Furthermore, pre-conditioning strategies with different agents could improve the efficacy of cell therapy. This study compares the effects of an anti-inflammatory and antioxidant agent, melatonin, on protection of bone marrow-derived MSCs [BMSCs] and adipose tissue-derived MSCs [ADSCs]