Comparison of oral versus intravenous proton pump inhibitors in preventing re-bleeding from peptic ulcer after successful endoscopic therapy

ABSTRACT

Background: Proton pump inhibitors [PPIs] are now widely prescribed for the management of patients with acute upper gastrointestinal bleeding; although its optimal dose and route of administration has remained a controversial issue. The aim of this study was to assess the clinical effectiveness of high dose oral versus intravenous [IV] PPI after successful endoscopic therapy in patients with bleeding peptic ulcer disease