Golgi protein 73 versus serum a-fetoprotein as tumor markers for hepatocellular carcinoma in patients with hepatitis C cirrhosis

ABSTRACT

Background/aim Hepatocellular carcinoma [HCC] is categorized as the firth most common type of malignancy and the third most common cause for cancer-related mortality. HCC has been growing in Egypt, with a doubling in the incidence rate in the previous 10 years owing to high prevalence of hepatitis C virus [HCV] in Egypt. Approximately 21% of Egyptian patients have cirrhosis, so the incidence of HCC is increasing. This work was to compare the diagnostic validity of Golgi protein 73 [GP-73] level versus a-fetoprotein [AFP] as tumor markers in HCC on top of HCV-related cirrhosis