Effect of boswellia carterii birdw on carbohydrate metabolism in diabetic male albino rats

ABSTRACT

In the current study, thirty male adult albino rats were used to investigate the effect of Boswellia Carterii Birdw [BCB] on carbohydrate metabolism in alloxan-induced diabetes. Rats were divided into three equal groups, control, diabetic non treated and diabetic BCB treated groups. After thirty days of treatment five rats of each group were sacrificed and the others were left without any additional treatment for another 15 days [recovery period] then were sacrificed. The body weight of each rat was determined at the beginning and the end of each period. Blood glucose, serum insulin and liver glycogen were determined for each rat at the end of each period. It was noticed that B.C.B treatment led to a significant improve in the decreased body weight, hyperglycemia, hypoinsulinemia, decreased liver glycogen caused by alloxan. And this improvement was also seen after the recovery period. B.C.B treatment led also to marked improvement in the histopathological degenerative changes in the beta cells of islets of Langerhans caused by alloxan after both the treated and recovery periods