Histopathological studies on some vital organs of mice exposed to extremely low frequency magnetic field

ABSTRACT

Twenty five male Swiss albino mice were used in this study to detect the effect of extremely low frequency magnetic field [ELFMF] 2 milli Tesla-50 Hertz [2 mT,50 Hz] 8 hours/day at different time intervals. Mice were divided into five groups, control group and 4 treated groups, two groups represented the direct effect of [ELFMF] and the other two represented the late effect. The direct effect groups were sacrificed direcly after the end of exposure to [ELFMF], while the late effect groups were sacrificed after certain duration period of the exposure away from [ELFMF]. In the present work, histopathological studies revealed severe degeneration changes in kidney, spleen and testes of all groups of mice direct and late effect groups and no sign of complete recovery could be detected in the late effect groups. Glomerular volume, number of glomeruli, relative glomerular blood volume [RGBV] of the kidney; and the mean number cells of spermatogenesis cells of the testes were calculated in control and treated groups. The histopathological changes observed in the kidney, spleen and testes of treated mice were less in direct effect groups than that observed in late effect groups