Comparison between the effect of ozone and vitamin C in treatment of diabetes mellitus

ABSTRACT

Objectives: There is strong evidence that diabetes results a state of oxidative stress and that reactive oxygen species contribute to the production of insulin resistance, ?-cell dysfunction and both the microvascular and macrovascular long-term complications of diabetes. Antioxidants are used as supportive therapy in the treatment of DM, so, we use ozone and vitamin C to study if they can regulate the oxidative complications of DM