Congenital heart diseases in noonan's syndrome - mitral valve anomalies: important cause of left ventricular outflow tract obstruction

ABSTRACT

Background: Noonan's Syndrome [NS] is a common genetic disorder associated with congenital heart disease. It is an autosomal dominant. Cardiac defects are found in 50-60% of cases of this syndrome. Ventricular outflow obstruction in the form of pulmonary valvular stenosis and hypertrophic cardiomyopathy [HOCM] is the most common congenital heart condition. Apart from HOCM, mitral valve anomalies are also associated with left ventricular outflow obstruction