Evaluation of glycated albumin to glycated hemoglobin ratio as a predictor for esophageal varices and its risk of bleeding

ABSTRACT

Background: Variceal hemorrhaging due to portal hypertension is a severe complication of liver cirrhosis. Although several biomarkers have been reported as predictors of the presence of varices, it is still difficult to assess the risk of variceal bleeding without esophagogastroduodenoscopy [EGD]. The ratio of glycated albumin [GA] to glycated hemoglobin [HbA1c] was reported to increase with the progression of liver fibrosis. The aim of the study was to investigate whether the GA/HbA1c ratio is related to the severity and bleeding risk of the varices