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Association of the wnt3 variations and the risk of non-syndromic cleft lip and palate in a population of iranian infants
AJMB-Avicenna Journal of Medical Biotechnology. 2018; 10 (3): 168-172
em Inglês | IMEMR | ID: emr-202060
ABSTRACT

Background:

Nonsyndromic cleft lip and/or palate [NSCL/P] is the most common orofacial birth defect, often attributed to ethnic and environmental differences. Up to now, linkage analyses and genome-wide association studies have identified several genomic susceptibility regions for NSCL/P. The WNT genes including WNT3 are strong candidates for NSCL/P, since they are involved in regulating mid-face development and upper lip fusion. This study tested association of the WNT3 polymorphisms, rs- 3809857 G/T and rs9890413 G/A, with the risk of NSCL/P in a population of Iranian infants
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Índice: IMEMR (Mediterrâneo Oriental) Idioma: Inglês Revista: Avicenna J. Med. Biotechnol. Ano de publicação: 2018

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Índice: IMEMR (Mediterrâneo Oriental) Idioma: Inglês Revista: Avicenna J. Med. Biotechnol. Ano de publicação: 2018