Role of leptin in non-alcoholic fatty liver disease [NAFLD]

ABSTRACT

Abstract The role of steatosis in the pathogenesis of chronic liver disease [CLD] is now believed to form part of a continuum in non alcoholic fatty liver disease [NAFLD]. One of the unconventional areas in which leptin is now receiving great attention is liver disease. Several published studies indicate that circulating leptin is increased in cirrhosis, HCV and NASH. The aim of this study was to investigate the role of leptin in NAFLD, by measuring the serum leptin level and correlating it with biochemical markers of liver disease and the result of liver biopsy in chronic hepatitis C [CHC] patients