[Evaluation of the HI-6 abillity on reversal or prevention of paraoxon-induced changes in the function of Chichen Biventer cervices nerve-muscle preparation]

ABSTRACT

Background: Paralaysis of skeletal muscles, which can lead to paralysis of respiratory muscles and death, is one of the most toxic effects of organophosphates [Ops], and oximes are almost the only known antidotes that can reverse or prevent such toxic effects. In the present research work, possible reversal or preventive effect of different concentrations of the relatively new oxime [Hl-6] on paraoxon-induced changes on function of skeletal muscle of chicken biventer cervices [CBC] nerve- muscle preparation were studied using twitch tension recording technique