Effectiveness of the non-steroidal ecdysone mimic, RH-5849 for the control of musca domestica vicina

ABSTRACT

The new non-steroidal ecdysone mimic, RH-5849 [1, 2-benzoyl-1-tert-butylbenzohydrazine] was investigated, its biological actions were evaluated in the laboratory against a susceptible strain of Musca d. vicina. The larvae of 1-day old and of 4-day-old were fed on diets treated with different concentrations of the compound. RH-5849 shortened the larval and pupal durations and induced the initiation of premature lethal moult. The pupation rate was highly affected, where it was reduced to 46.7% at a concentration rate of 250 ppm. Also, the adult emergence was drastically blocked by the action of RH-5849 where its percentage was decreased to 42.9 at 250 ppm. In regard to the fecundity and egg viability, RH-5849 induced a cessation of oviposition in females produced from 1-day-old and from 4-day-old larvae fed on diets treated with 160 and 200 ppm, respectively. In addition, RH-5849 halted the larval and pupal growth, where the untreated pupae were generally heavier than those produced from treated larvae