Homocysteine in type II diabetes mellitus, its relation to ischemic heart disease and smoking

ABSTRACT

To study the homocysteine level in type II diabetes mellitus and its relation to ischemic heart disease [IHD] and smoking habits. Thirty one type diabetic patients and 10 healthy normal controls were evaluated by measurement of FBS, HbA1c and fasting homocysteine level. All patients and controls had full clinical examination and investigated for the presence of IHD. Homocysteine level in type II diabetic patients was higher [p<0.0001] than in controls with positive correlation to FBS and HbA1c level. There is significantly high level of homocysteine [P<0.000 1] in type II diabetic patients with IHD compared to the patients without, there was also a significant difference in homocysteine level in diabetic pateints between smokers and non smokers [P<0.0001]