Correlation of sonographic and Doppler findings with histopathological findings in premenopausal and postmenopausal bleeding

ABSTRACT

This study was carried on 50 patients complaining of abnormal uterine bleeding, 40 of them were suffering from premenopausal bleeding and the other 10 cases were complaining of postmenopausal bleeding. Transvaginal ultrasound [TVS] to measure the endometrial thickness and Pulsed - colour Doppler [PCD] of the uterine artery was clone for all cases. Endometrial sampling using vabra aspiration was then done for all the cases and the specimens were subjected to histopathological examination. The sonographic and colour Doppler findings were correlated with the histopathologic findings. From this study it was found that the uterine artery resistance index [0.93 +/- 0. 17] and pulsatility index decrease [1.87 +/- 0.22] as the pathological process increases. Also the endometrial thickness increases with the increase in the degree of the pathological condition [9.51 +/- 3.21] mm in premenopausal bleeding compared to 10.83 +/- 6.79mm in postmenopausal bleeding. It was concluded [rum this study that TVS and PCD are very reliable complementary procedures for screening and diagnosis of the etiology of abnormal uterine bleeding because TVS reports about endometrial morphology while PCD is concerned about endometrial vascularity which reflects the nature of the pathology rather than its gross anatomical features