Abnormal glucose screening test followed by normal glucose tolerance test and pregnancy outcome

The present study was conducted explore the pregnancy outcome of patients with abnormal glucose screening test followed by normal glucose tolerance test. In Combined Military Hospital [CMH], Rawalpindi, a study was made to compare the complication of pregnancy, infant weight, placental weight and neonatal morbidity in women with and without abnormal glucose screening test, it was performed between July 1998 and June 2000. Hundred postnatal files from each group were analyzed. The Chi square test, and test for comparison of proportion were the statistical test used. Although women with abnormal glucose screening test were older, there was no evidence in this study that increasing parity is a risk factor for abnormal glucose screening test. Candidiasis and polyhydramnios was significantly more frequent in the group with abnormal glucose screening test. The women with abnormal screening test were at higher risk for elective cesarean section, whereas the number of emergency cesarean section and instrumental deliveries was not significantly different. The mean birth weight of infants in the abnormal glucose screening test group was higher and also, macrosomia was significant more frequent in this group. The mean weight of placenta from women with abnormal glucose screening test was higher than that of placenta from women with normal glucose screening test. The results of this study are consistent with the previous reports that even minor abnormalities of glucose metabolism without gestational diabetes are a significant risk factor for fetal overgrowth and its attendant problems