Comparison of six irradiation techniques for delivering hypofractionated whole-breast radiotherapy with a simultaneous integrated boost after breast-conserving surgery

ABSTRACT

Background: to compare the following techniques for hypofractionated whole-breast irradiation [WBI] with simultaneous integrated boost [SIB] after breast-conserving surgery [BCS] three-dimensional conformal radiation therapy plus electron boost [3DCRT-EB], intensity-modulated radiation therapy [IMRT] plus EB [IMRT-EB], field-in-field IMRT plus EB [FIF-IMRT-EB], FIF-IMRT plus IMRT boost [FIF-IMRT-IB], IMRT plus IMRT boost [IMRT-IB], and volumetric-modulated arc therapy [VMAT] plus VMAT boost [VMAT-VB]