[ study of relationship between PCNA and Ki67 [cell proliferation markers] and histologic parts of Wilms's tumor]

ABSTRACT

Background: Wilm's tumor is the most frequent primary renal neoplasma in pediatric age group. Classically it is composed of three histologic parts Blastemal, Epithelial and stromal. Different factors are implicated as prognostic determinants. Nowadays special attention is paid to proliferation markers for determining the biologic behavior of tumors. In this study we tried to ascertain the proliferative index of 22 cases of Wilm's tumor in our center who have had rather good follow up [at least two years]