[ effect of retinoic acid on human embryonic stem cells with and without rosette morphology]

ABSTRACT

Introduction: Human Embryonic Stem [hES] Cells are pluripotent cells derived form the inner cell mass of blastocyst. These unique cells have the potential to form virtually any cell type in the body and can be propagated in vitro indefinitely in an undifferentiated state. This study was initiated to assess the effect of retinoic acid [RA] on hES cells with and without rosette morphology [neuroectodermallike cells]