Immunoglobulins and cardiac enzymes interrelationship in acute myocardial infarction

ABSTRACT

This study included 25 patients [16 males and 9 females] with acute myocardial infarction with age range from 40 to 65 years. We assessed the serum level of C K and LDH. IgA and IgG within the first 24 hours of the onset of infraction we found a good significant correlation between CK and IgG [mean 323 +/- 79.96 Vs 208 +/- 77.6 u/ml with r = 0.83, P<0.05]. Also there is a significant correlation between CK and IgA [mean 167 +/- 29.4 u/ml r = 0.72, P<0.05]. While the LDH [mean 191 +/- 65.76 u/ml] show a high significant correlation with IgA [r =0.90 and P<0.05] also it correlated significarnty with IgG [r =0.76, P<0.05]. Also we found less significant correlation between the amplitude of ST segment changes and IgA. [r =0.66 and IgG, r =0.56]. However there was no any correlation between the depth or duration of the Q wave and any of the cardiac enzymes or immunoglobulins .So we can conclude that C K. IgA and IgG are significant elevated than normal in almost all patients. IgG is elevated early even earlier than CK and show a close relation to CK while is closely related to LDH