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mutual interrelation between major surgical trauma and the immunological response as measured by spontaneous rosette formation
Medical Journal of Cairo University [The]. 1982; 50 (4): 429-34
em Inglês | IMEMR | ID: emr-2306
ABSTRACT
The cell mediated immune response was studied by rosette formation in 24 patients before and after major surgery. Nine patients [37.5%] showed preoperative reduction in the number of T lymphocytes, and these patients continued to be suppressed postoperatively. Out of the other 15 patients, nine cases [60%] developed a de novo postoperative fall in their T lymphocyte population; this can be attributed to operative trauma. Among the overall 18 immunosuppressed patients in the postoperative period, 12 developed infection, 5 had other complication, while one died. This last patient had both preoperative and postoperative reduction of T lymphocytes. Infection was encountered in all the 9 patients with preoperative immunodepression, but only in 3 out of the 9 patient who developed postoperative suppression; a finding that may point to greater role of preoperative reduction of T lymphocytes than surgical trauma in the pathogenesis of postoperative morbidity
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Cirurgia Geral / Técnicas Imunológicas Idioma: Inglês Revista: Med. J. Cairo Univ. Ano de publicação: 1982

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Cirurgia Geral / Técnicas Imunológicas Idioma: Inglês Revista: Med. J. Cairo Univ. Ano de publicação: 1982