Experimental ulcerative herpetic keratitis: Humoral immune response and its role in corneal protection
EJMM-Egyptian Journal of Medical Microbiology [The]. 1992; 1 (2): 122-127
em Inglês
| IMEMR
| ID: emr-23439
ABSTRACT
Twenty five rabbits were inoculated with HSV type [1] to estimate the humoral immune response and corneal protection. The serum neutralizing antibody could be detected 15 days after inoculation. Ig[G], Ig[A] and Ig[M] specific to the virus were detected by immunofluorescence. Only corneae of 2 out of 14 immunized rabbits developed corneal ulcers, when challenged with the virus, as compared to 5 non-immunized that developed ulcer. The 2 immunized rabbits that developed corneal ulcers showed complete healing in 3 days to treatment with trifluorotrhymidine as compared to 6 days for the non-immunized control group [5 rabbits]
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Coelhos
/
Úlcera da Córnea
/
Trifluridina
/
Herpesvirus Humano 1
/
Córnea
/
Imunidade
/
Formação de Anticorpos
Limite:
Animais
Idioma:
Inglês
Revista:
Egypt. J. Med. Microbiol.
Ano de publicação:
1992
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