Evaluation of ceftazidime antimicrobial activity in infections caused by burns

ABSTRACT

In vitro evaluation of ceftazidime antimicrobial activity in infections caused by burn and its comparison to the other antibiotics is presented. In vitro tests for susceptibility to ceftazidime and other antibiotics were carried out on 744 bacterial strains collected from burn infections. The results have shown that generally ceftazidime was more active against Pseudomonas aeruginosa and other gram-negative bacilli like Klebsiella pneumoniae, Escherichia coli, and Proteus than amikacin, gentamicin, tobramycin, carbenicillin, kanamycin, and streptomycin in terms of potency and activity. In addition, and according to our in vitro studies we suggest that ceftazidime could be considered a valuable alternative to other antibiotics in the treatment of burn infections caused by P. aeruginosa and other gram- negative bacilli