Is carcinoma of the breast in Egyptian females highly aggressive?

ABSTRACT

A new technique has been introduced to detect the degree of aggression of breast cancer, this is the estimation of the DNA content of malignant tumours of the breast by cytophotometry to determine the ploidy status of the tumour. This can give a good hint about the behavior of the disease. The cellular DNA content of 61 female patients, chosen at random, and suffering from carcinoma of the breast was determined by static cytophotometry using modified Feulgen stain. This showed that 65.57 percent of the tumours were aneuploid while 34.43 percent were diploid. The disease free interval and the total survival were longer for diploid than for aneuploid patients