[Tuberculosis and acquired immunodeficiency syndrome]

ABSTRACT

From January 1987 to July 1990, 16,2% of patients followed with Human Immunodeficiency Virus [HIV] infection, of which six were ill [all with AIDS], had tuberculosis. Pulmonary tuberculosis was present in four patients [66,6%], and extrapulmonary tuberculosis in six. The extrapulmonary infections were located in the mediastinal lymph nodes in two cases, the peripheral lymph nodes in two cases, and in the pleura in two cases. Pulmonary infection was multilobar in four cases with cavitary infiltrates in one case. An intradermal skin test, using 10 TU PPD, was positive in only one case. The diagnosis of tuberculosis was confirmed by evidence of Mycobacterium Tuberculosis [MT] in direct examination in three cases, by cultures in the same three cases, and histology in four cases. Preliminary results of antibacterial treatment were favorable in five patients. However, these five patients died within an average of twelve months after diagnosis of tuberculosis, corresponding with the CDC which includes extrapulmonary tuberculosis in their case definition of AIDS. A study of a larger series would allow clarification of the epidemiological aspects of tuberculosis associated with HIV infection in Morocco