Diabetic nephropathy

ABSTRACT

Diabetic Nephropathy is the main cause of mortality in approximately 40-45% of all Insulin-dependent diabetics, appearing between 10th 30th years of onset of diabetes [1, 24, 28] with a suggested male preponderance [24]. Non Insulin-dependent diabetics are also affected by this sinister complication but the incidence is lower and other complications of diabetes dominate over it as cause or mortality. The intensity of problem can be well imagined by the fact that in United States 25% of total end-stage renal disease id due to diabetes costing about one dollars each year [I] while in U.K 11.1% of total intake of ESRF patients accepted for renal replacement therapy was due to diabetic nephropathy in 1984 and this proportion is rising [28] and in Europe 10% of annual intake have ESRF due to Diabetes