Pediatric Hodgkin's disease in upper Egypt

ABSTRACT

48 children younger than 16 years were diagnosed, staged and treated in Radiotherapy, Pediatric and Surgical Departments [Assiut University Hospital]. During the period from January, 1987 to December 1991 Most of cases were in their first decade [65.4%]. Male predominated representing 72.92% and male to female ratio was 2.691. Mixed cellularity occurred, in 52.08%, nodular sclerosing in 14.5%, lymphocytic predominance in 27.08% and lymphocytic depletion in 6.26%. More than one half of the cases [56.24%] were in stage III and IV at presentation. The mediastinum was involved in 4.1%.The treatment strategy was radiotherapy for early cases and chemotherapy for late cases. The treatment responses were excellent in the early cases and had in the late cases. This could be attributed to high tumour burden as well as malnutrition