Intrauterine insemination [IUI] using swim-up technique or percoll gradient technique versus timed intercourse in the management of unexplained infertility

ABSTRACT

Forty-eight patients with unexplained infertility were subjected to 3 treatment protocols. They were randomly divided into 3 groups. Group I comprised 13 patients who were treated by induction of superovulation and timed intercourse through 17 treatment cycles. Group II included 16 patients who were treated by induction of superovulation and IUI using husbands washed sperm prepared by the swim-up technique through 19 treatment cycles. Group III. on the other hand, included 19 patients who were similarly treated but with IUI utilizing Percoll gradient technique, through 23 treatment cycles. The clinical pregnancy rates/treated cycles were 5.9% in the first group, 10.5% in the second group and 13% in the third group. Induction of superovulation and IUI with husbands capacitated sperm especially using Percoll gradient technique may he beneficial for treatment of patients with unexplained infertility