effect of clonidine hydrochloride [Catapres] on mepivacaine spinal anesthesia

ABSTRACT

To study the effect of clonidine hydrochloride [catapress] on mepivacaine subarachnoid block, 40 patients were divided into 2 groups. The first [control group] received mepivacaine alone [120 mg] and the other [clonidine group] received mepivacaine [120 mg] plus clonidine [150 mg] intrathecally. It was found that clonidine potentiated and prolonged the duration of sensory and motor blockade and can cause sedation of the patients without a greater effect on the hemodynamics than that produced by the local anesthetic alone