Effect of honey on tracheobronchial tree of adult male guinea pigs

ABSTRACT

The effect of honey on the bronchoconstriction induced by histamine [0.5%] and acetylcholine [4%] aerosols in normal conscious guinea pigs, as well as its antianaphylactic effect on sensitized guinea pigs exposed to the antigen [5% ovalbumin aerosol] have been evaluated. Pretreatment with honey [3 g/kg] prolonged the preconvulsive time of normal conscious guinea pigs exposed to histamine, acetylcholine aerosols, or sensitized guinea pigs exposed to the antigen [5% ovalbumin] aerosol. The effect in the latter one is better than the first two types. This denoted that honey can be used for treatment of bronchial asthma due to its antagonistic effect to hypersensitivity reactions