Pattern of certain enzyme activities in serum and urine in different types and stages of bilharzial patients

ABSTRACT

The study comprised 116 bilharzial adult male patients with age range 18-65 years. None of the selected individuals was complaining from other diseases and proved to have no treatment for bilharziasis prior to their inclusion in this study. Data for age, weight and degree of liver and /or spleen enlargement were registered. Besides the bilharzial cases, 15 healthy adult normal individuals [group C] with the same age range as control, were included in the study. The bilharzial cases were a] 15 patients with hematobiasis [group H], b] 74 subjects of mansoniasis, further subdivided into 4 subgroups [23 cases in the early stage of the disease where the liver was not enlarged and the spleen was not palpable [m1], 21 subjects in the 2nd stage of the disease [m2], the main clinical feature was the occurrence of hepatomegaly, the spleen was not enlarged, 15 cases in the 3rd stage of the disease [m3], the hepatosplenomegalic stage of bilharziasis without ascites, 15 subjects in the 4th stage of the disease [m4], hepatosplenomegaly with ascites], c] 27 cases with mixed schistosomiasis were subdivided into 4 subgroups 14 cases of mixed infection in early stage of mansoniasis [Mix1], 5 cases with hepatosplenomegalic stage of the disease [Mix2], 4 bilharzial subjects presented the hepatosplenomegaly without ascites [Mix3], 4 patients with hepatosplenomegaly and ascites [Mix4]. The results of this study were given in detail