Effects of water pollution with organophosphate [cythion] and organochloride [hexadrin] compounds on the antioxidant enzyme system in carp liver

ABSTRACT

The present work discussed the response reactions of tissue antioxidant enzymes in fishes as a model system upon exposure to organophosphate [Cythion] and organochloride [Hexadrin]. In the present experiments, changes of antioxidant enzyme activities and lipid peroxidation were studied in carp livers exposed to two different concentrations of these compounds. Antioxidant enzymes were studied. Addition of Hexadrin in water at SC or LC 50 concentrations induced significant [P <0.01] increase in t-SOD and GR-ase enzyme activities as well as in GSH, OH and LP levels of carp liver. Also, the activity of t-SOD, GP-ase and GSH was significantly icreased following exposure to SC [P <0.05] or LC 50 [P <0.01] concentration of Cythion