Synthesis and biological activity some new thiadiazolo, triazolo and fused s-triazolo [3,4-b] -1,3,4-thiadiazolo-coumarins

ABSTRACT

In this study, some new thiadiazolo triazolo and fused s-triazolo [3,4-b]-1,3,4-thiadiazolo-coumarins were prepared from [4,8-dimethyl- 7-coumarinyloxy] acetic acid hydrazide via different intermediates, and evaluated for their pharmacological activities. Some of the tested compounds exhibited CNS depressant activity in the experimental animals