Spectrophotometric studies on determination of sulphadimidine

ABSTRACT

Spectrophotometric studies have been made for the determination of Sulfadimidine by reacting with some aldehydes, as salicylaldehyde and cinnamaldehyde. The color intensity of the formed Schiff bases was found to depend upon the nature and concentration of acid and aldehyde used. The optimum temperature for color development was 50C and heating time was 30 minutes. The procedures were developed for determination of sulfadimidine in presence of sulfanilamide, sulfaguanidine and sulfasomidine. The method has been successfully used for the spectrophotometric determination of sulfadimidine alone and in the presence of some sulfonamides